Xolboboyeva Shakhnozakhon Asadullaevna worked as a teacher of internal medicine at the Fergana City Medical College No. 2 from 2000 to 2016. 2019-2021. Teacher at the Fergana Department of Advanced Training and Specialization of Secondary Medical Workers and Pharmacy Workers of the Fergana City. 2021-2022. Assistant at the Department of Internal Medicine No. 1 of the Fergana Public Health Medical Institute. 2022-2023. Assistant at the Department of Facultative Therapy of the Fergana Public Health Medical Institute. 2023-2024. Assistant at the Department of Internal Medicine of the Central Asian Medical University. 2025. Senior Lecturer at the Department of Phthisiology and Pulmonology, Metabolic Diseases of the International Medical University of CAMU.
Since 2025, she has been working as a teacher of folk medicine at the Faculty of Medicine of the International Medical University of Central Asian Medical University.